This project builds on existing close collaboration between the network of collaborating hematology centers in Greece. It also represents the extension of our relevant ongoing activities focused on the creation of a standardized clinic-biological data registration system for patients attended at the Hematology Department and HCT Unit of the G. Papanicolaou Hospital in Thessaloniki, Greece, where the proponent of the present proposal holds the position of Head of the Laboratory of Molecular Diagnostics and Scientific Advisor for Basic and Translational Research. As mentioned in the preceding paragraph, results from the pilot phase of this initiative have already been published/presented, offering proof of concept for the feasibility and scope of the proposal. The system will essentially be based on a systematic cataloguing and clear understanding of the data types to be collected, their categories, their relationships, and their properties. The first milestone will be performed through face-to-face meetings between (bio)informatics and hospital staff as well as a constant exchange of a purpose-built electronic spreadsheet, which contains the data types and structures, i.e. in different columns and sheets.